Dr. Nadella is involved in the research, preparation and prosecution of U.S. and International patent applications. She also contributes to the preparation of non-infringement and patentability opinions and has experience in conducting due diligences, and freedom-to-operate and inventorship analyses. Her areas of technical experience include molecular biology, protein biochemistry, X-ray crystallography, enzymology, neuroscience, biotechnology, immunology, and cell biology.

Prior to joining Sterne Kessler, Dr. Nadella's research was primarily focused on determining the three-dimensional structure of a protein involved in axon guidance, MICAL (Molecule Interacting with Cas-L). After obtaining structural data pertaining to this protein, she was able to establish spectrophotometric assays to monitor MICAL's catalytic activity. The protein studied is critical for proper nerve path-finding in the embryonic and adult nervous systems.

During her graduate school career, Dr. Nadella was a tutorial assistant for both medical and graduate students. Dr. Nadella is also a registered volunteer donor for the National Marrow Donor Program.

Technical Publications

Settle M, Gordon MD, Nadella M, Dankort D, Muller W, Jacobs JR. Genetic identification of effectors downstream of Neu (ErbB-2) autophosphorylation sites in a Drosophila model. Oncogene. 2003 Apr 3;22(13):1916-26.

Nadella M, Bianchet MA, Gabelli SB, Barrila J, Amzel LM. Structure and activity of the axon guidance protein MICAL. PNAS. 2005 Nov 15;102(46):16830-16835

Nadella M, Bianchet MA, Gabelli SB, Amzel LM. A Redox Reaction in Axon Guidance: Structure and Enzymatic Activity of MICAL. NSLS Science Highlight. 2006 Mar 15

Mohan S., Tse C.M., Gabelli S.B., Sarker R., Cha B., Fahie K., Nadella M., Zachos N.C., Tu-Sekine B., Raben D., Amzel L.M., and Donowitz M. NHE3 activity is dependent on direct phosphoinositide binding at the N-terminus of its intracellular cytosolic region J. Biol. Chem. First Published on August 24, 2010 as Manuscript M110.165712